Our objective is to assess if tamoxifen treatment is associated with an increase in Introduction
Standard treatment for premenopausal women with hormone receptor-positive breast cancer is tamoxifen for 5-10 years, with or without ovarian suppression [ 8 ]
Tamoxifen is a hormone therapy drug to treat breast cancer in women and men
Background: Treatment of advanced ovarian cancer results in a high objective response rate (> 70% to 80%), but disease recurs in most patients
The UCLA Health women’s cancer research team in OBGYN played a pivotal role in a clinical trial that led to the FDA granting accelerated approval of the first
(Hormone-positive breast cancer is
Ovarian cancer (OC) has the worst prognosis among gynecological malignancies, most of which are found to be in advanced stage
The response rate to tamoxifen in small phase II studies of patients with recurrent ovarian cancer ranges between 3
Tamoxifen has changed the landscape of breast cancer treatment and prevention since its introduction in the late 1960’s
Maintenance therapy must balance prevention of disease recurrence with cumulative
Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 10-year analysis of the ATAC trial
240-760-6600
Hormone therapies used in breast cancer treatment act as “anti-hormone” or “anti-estrogen” therapies
Data from two studies evaluating the use of tamoxifen for the treatment of advanced ovarian cancer suggest that tamoxifen may be beneficial for the treatment of this condition Hatch 1991, Markman 1996
Several United States and
There are many things to consider, however, with prophylactic surgery, including pain, recovery time, whether
It is a treatment that adds, blocks or removes hormones
Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study
2017; 52: 82-90
The most proven method for the prevention of ovarian cancer in women who carry a deleterious BRCA1 or BRCA2 mutation is RRSO
Stage 2: Cancer is found elsewhere in the pelvic region
For this reason, many trials on adjuvant therapy in premenopausal women subsequently focused
Tamoxifen (TAM) is a drug commonly used in patients with breast cancer
Although various surgical techniques and chemotherapies have been applied to the treatment of ovarian carcinoma, the prognosis remains poor